Leading Causes of Death in the United States, 2016

Cause Deaths
Heart Disease 635,260
Cancer 598,038
Accidents (Unintentional Injuries) 161,374
Chronic Lower Respiratory Diseases 154,596
Stroke 142,142
Alzheimer's Disease 116,103
Diabetes 80,058
Flu/Pneumonia 51,537
Nephritis, Nephrotic Syndrome, and Nephrosis 50,046
Suicide 44,965

Source: Centers for Disease Control and Prevention, National Center for Health Statistics. Leading Causes of Death.